Wow ...the games are completely dissimilar, so it's hard to make a comparison. Also, this is an opinion question, so it should probably be a pick. It's like asking "What's better? Eating, atau getting a paycheck?"
Connect four is a two-player game that takes about five minit to play. Scene it? is a party game that takes at least half an jam and requires a TV and DVD player (or online video game system). If anda like a big group experience - and can gather a big group of people fairly regularly - then Scene it? is better. If anda prefer a quick game and/or anda only have one person anda can play with, then Connect Four is better.